Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL5672510 | 0.85 | LMNA (0.46) | LMNAL3MBTL1KMT2ANPSR1KDM4E | |
| SCHEMBL30192808 | 0.84 | LMNA (0.61) | LMNAL3MBTL1PABPC1KMT2AATM | |
| SCHEMBL5286396 | 0.84 | LMNA (0.61) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Hydrochloric Acid SCHEMBL5155050 | 0.83 | LMNA (0.65) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Bromide SCHEMBL17105097 | 0.83 | LMNA (0.62) | LMNAL3MBTL1PABPC1KMT2AATM | |
| SCHEMBL5074160 | 0.82 | LMNA (0.55) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL3629145 | 0.82 | KCNH2 (0.44) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL5674195 | 0.81 | L3MBTL1 (0.56) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL6516307 | 0.81 | KCNH2 (0.40) | LMNAL3MBTL1PABPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL5671407 | 0.80 | LMNA (0.43) | LMNAL3MBTL1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373552-A4 | NOVEL AGENTS FOR REPLACEMENT OF NAD+/NADH SYSTEM IN ENZYMATIC RACTIONS | UNIV CALIFORNIA (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20040235084-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | ENERGY, UNITED STATES DEPARTMENT OF | 2004-11-25 | — | — | US | disclosed |
| US-6716596-B2 | biomimic cofactor; 3-substituted pyridium compounds; nicotinamides N-substituted with benzyl or polyoxyethylene glycol derivatives; bipyridyl rhodium hydride complex catalyst for reduction of the cofactor; polymer matrix; economical in large scale; biosensor or a chemical membrane bioreactor | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-06 | — | — | US | disclosed |
| EP-1373552-A2 | NOVEL AGENTS FOR REPLACEMENT OF NAD+/NADH SYSTEM IN ENZYMATIC RACTIONS | The Regents of the University of California (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20030022266-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | ENERGY, U.S. DEPARTMENT OF | 2003-01-30 | — | — | US | disclosed |
| WO-2002072869-A2 | NOVEL AGENTS FOR REPLACEMENT OF NAD+/NADH SYSTEM IN ENZYMATIC RACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022266-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | NQO1, NADK, ME2 | LMNA 3814/4885L3MBTL1 4651/4885PABPC1 3978/4885 |
| US-20040235084-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | NQO1, NADK, ME2 | LMNA 3814/4885L3MBTL1 4651/4885PABPC1 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.