Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LSS | P48449 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898907 | 0.85 | PKM (0.46) | NR1I2ALDH1A1HTTLMNA | |
| SCHEMBL9063914 | 0.85 | SMN1; SMN2 (0.34) | LSSL3MBTL1ALDH1A1HTTLMNA | |
| SCHEMBL7929627 | 0.84 | NR1I2 (0.47) | NR1I2GAAL3MBTL1ALDH1A1RARB | |
| SCHEMBL5897070 | 0.80 | GAA (0.50) | NR1I2GAAALDH1A1CYP19A1 | |
| SCHEMBL3424272 | 0.79 | CYP1A2 (0.39) | GAALSSALDH1A1LMNA | |
| SCHEMBL11896656 | 0.79 | MLYCD (0.32) | ALDH1A1 | |
| SCHEMBL3428089 | 0.79 | L3MBTL1 (0.40) | L3MBTL1 | |
| SCHEMBL13310001 | 0.79 | EGFR (0.34) | ALDH1A1 | |
| SCHEMBL8899051 | 0.79 | TSHR (0.41) | ALDH1A1HTTLMNA | |
| SCHEMBL8161015 | 0.78 | NR1I2 (0.43) | NR1I2GAALSSL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095966-B1 | Process for the modification of a material surface | NOVARTIS AG (CH) | 2006-01-11 | — | — | EP | disclosed |
| EP-1395302-B1 | BOTTLE-BRUSH TYPE COATINGS WITH ENTANGLED HYDROPHILIC POLYMER | NOVARTIS AG (CH) | 2005-02-02 | — | — | EP | disclosed |
| US-6835410-B2 | Graft polymer overcoating | NOVARTIS AG (CH) | 2004-12-28 | — | — | US | disclosed |
| EP-1395302-A1 | BOTTLE-BRUSH TYPE COATINGS WITH ENTANGLED HYDROPHILIC POLYMER | Novartis AG (CH) | 2004-03-10 | — | — | EP | disclosed |
| EP-1095711-B1 | Process for coating a material surface | NOVARTIS AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| US-6586038-B1 | Modification of surface of a biomedical material or article, especially an extended-wear contact lens, articles are coated with polymer having a \"bottle-brush\" type structure composed of tethered \"hairy\" chains | NOVARTIS AG (CH) | 2003-07-01 | — | — | US | disclosed |
| US-20030008063-A1 | Bottle-brush type coatings with entangled hydrophilic polymer | ALCON INC. (CH) | 2003-01-09 | — | — | US | disclosed |
| WO-2002094331-A1 | BOTTLE-BRUSH TYPE COATINGS WITH ENTANGLED HYDROPHILIC POLYMER | NOVARTIS AG (CH) | 2002-11-28 | — | — | WO | disclosed |
| US-6468667-B1 | Ophthalmic molding | NOVARTIS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| US-6465056-B1 | GRAFT POLYMERIZING UNSATURATED HYDROPHILIC MONOMERS ONTO SURFACE OF POLYMER BRUSHES MODIFIED WITH POLYMERIZATION INITIATOR RADICALS; EXTENDED-WEAR CONTACT LENS COATED WITH A ?BOTTLE-BRUSH? TYPE POLYMER; WETTABILITY, WATER RETENTION | NOVARTIS AG (CH) | 2002-10-15 | — | — | US | disclosed |
| EP-0808222-B1 | PROCESS FOR THE FUNCTIONALISATION OF SURFACES | NOVARTIS AG (CH) | 1999-05-19 | — | — | EP | disclosed |
| EP-0800657-B1 | POLYMERS BASED ON BLOCK COPOLYMERS | NOVARTIS AG (CH) | 1998-11-25 | — | — | EP | disclosed |
| EP-0808222-A1 | PROCESS FOR THE FUNCTIONALISATION OF SURFACES | Novartis AG (CH) | 1997-11-26 | — | — | EP | disclosed |
| EP-0800511-A1 | FUNCTIONALISED PHOTOINITIATORS, DERIVATIVES AND MACROMERS THEREFROM AND THEIR USE | Novartis AG (CH) | 1997-10-15 | — | — | EP | disclosed |
| EP-0800657-A1 | POLYMERS BASED ON BLOCK COPOLYMERS | Novartis AG (CH) | 1997-10-15 | — | — | EP | disclosed |
| EP-0793541-A1 | NCO-TERMINATED VINYL TELOMERS | Novartis AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996020919-A1 | FUNCTIONALISED PHOTOINITIATORS, DERIVATIVES AND MACROMERS THEREFROM AND THEIR USE | NOVARTIS AG (CH) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996020796-A1 | PROCESS FOR THE FUNCTIONALISATION OF SURFACES | NOVARTIS AG (CH) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996020795-A1 | NCO-TERMINATED VINYL TELOMERS | NOVARTIS AG (CH) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996021167-A1 | POLYMERS BASED ON BLOCK COPOLYMERS | NOVARTIS AG (CH) | 1996-07-11 | — | — | WO | disclosed |