Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517662 | 0.87 | INSR (0.44) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9032110 | 0.83 | INSR (0.52) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| Iodide SCHEMBL3860161 | 0.79 | MAPT (0.61) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6512286 | 0.76 | INSR (0.44) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11516033 | 0.74 | INSR (0.68) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11516037 | 0.74 | INSR (0.68) | INSRHTTSMN1; SMN2TSHRALDH1A1 | |
| Iodide SCHEMBL31063723 | 0.72 | MAPT (0.61) | INSRHTTALDH1A1TDP1LMNA | |
| SCHEMBL11516326 | 0.70 | MAPT (0.45) | INSRHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11748071 | 0.70 | MAPT (0.53) | HTTSMN1; SMN2ALDH1A1ACHECYP3A4 | |
| Iodide SCHEMBL31063860 | 0.69 | MAPT (0.47) | INSRHTTSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235549-B1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KGAA (DE) | 2006-11-29 | — | — | EP | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-6790239-B1 | COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-09-14 | — | — | US | claimed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | claimed |
| EP-1432394-A1 | AGENT FOR COLORING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2003030846-A1 | AGENT FOR COLORING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1235549-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-09-04 | — | — | EP | claimed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| WO-2001034106-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | claimed |
| EP-1235549-B1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KGAA (DE) | 2006-11-29 | — | — | EP | disclosed |
| US-7060109-B2 | Hair dyeing agents containing indigo derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGA A) (DE) | 2006-06-13 | — | — | US | disclosed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | disclosed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | disclosed |
| EP-1585489-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2001034106-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | disclosed |
| EP-0161789-B1 | CYANINE AND MEROCYANINE SPECTRAL SENSITIZING DYES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4701398-A | CYANINE AND/OR MEROCYANINE DYES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4614801-A | Direct positive dyes made from 3-indolizine carboxaldehyde | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | KRT18, CKAP4, KRTCAP2 | INSR 4850/4885HTT 1656/4885SMN1; SMN2 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.