Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976931 | 0.81 | ALDH1A1 (0.37) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL567366 | 0.79 | HTT (0.51) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL567608 | 0.79 | HTT (0.51) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL567494 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL567327 | 0.75 | GLA (0.47) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL536617 | 0.75 | GLA (0.47) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL9293963 | 0.73 | CTSK (0.47) | CTSKATMCYP3A4CYP2C9TSHR | |
| SCHEMBL938011 | 0.73 | ATM (0.57) | CTSKCTSSCTSLATMCTSB | |
| SCHEMBL19569920 | 0.73 | POLB (0.61) | CTSKCTSSCTSLATMALDH1A1 | |
| SCHEMBL15414625 | 0.73 | ATM (0.57) | CTSKCTSSCTSLATMCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035341-A1 | PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS | MINASOLVE (FR) | 2012-02-09 | — | — | US | disclosed |