SCHEMBL541845

SCHEMBL541845

CCO[C@H]([C@H](O)CO)[C@H](C=O)OOC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5676584 0.81 AKR1B1 (0.37) AKR1B1
SCHEMBL5834719 0.81 AKR1B1 (0.37) AKR1B1
SCHEMBL5676296 0.81 AKR1B1 (0.37) AKR1B1
SCHEMBL3441481 0.78 AKR1B1 (0.34) AKR1B1
SCHEMBL8002266 0.78 LMNA (0.39) AKR1B1
SCHEMBL8934913 0.77 LMNA (0.42) AKR1B1
SCHEMBL8934933 0.77 LMNA (0.42) AKR1B1
SCHEMBL18740409 0.76
SCHEMBL8025665 0.74 LMNA (0.38)
SCHEMBL9300148 0.74 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119790155-A Threose nucleic acid antisense oligonucleotide and method thereof 豪夫迈·罗氏有限公司 2025-04-08 CN claimed
CN-118434860-A Threose nucleic acid antisense oligonucleotide and method thereof 豪夫迈·罗氏有限公司 2024-08-02 CN claimed
US-20260146278-A1 Biological Substance Treatment Method, Reaction Detection Method, Biological Substance Treatment Apparatus, and Reaction Detection Apparatus JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2026-05-28 US disclosed
EP-4606907-A1 BIOLOGICAL SUBSTANCE TREATMENT METHOD, REACTION DETECTION METHOD, BIOLOGICAL SUBSTANCE TREATMENT APPARATUS, AND REACTION DETECTION APPARATUS Japan Science and Technology Agency (JP) 2025-08-27 EP disclosed
CN-119790155-A Threose nucleic acid antisense oligonucleotide and method thereof 豪夫迈·罗氏有限公司 2025-04-08 CN disclosed
CN-118434860-A Threose nucleic acid antisense oligonucleotide and method thereof 豪夫迈·罗氏有限公司 2024-08-02 CN disclosed
US-20240175020-A1 COMPOSITIONS OF MODIFIED TREMS AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2024-05-30 US disclosed
WO-2024085132-A1 BIOLOGICAL SUBSTANCE TREATMENT METHOD, REACTION DETECTION METHOD, BIOLOGICAL SUBSTANCE TREATMENT APPARATUS, AND REACTION DETECTION APPARATUS 国立研究開発法人科学技術振興機構 2024-04-25 WO disclosed
CN-117106887-A Compositions and methods for diagnosing and treating tuberculosis 塞弗德公司 2023-11-24 CN disclosed
CN-116635538-A Compositions and methods for diagnosing and treating tuberculosis 塞弗德公司 2023-08-22 CN disclosed
CN-116348767-A Method for diagnosing tuberculosis and distinguishing active tuberculosis from latent tuberculosis 西菲伊德公司 2023-06-27 CN disclosed
CN-106029887-A Materials and methods for treatment of pulmonary arterial hypertension 格拉斯哥大学理事会 2016-10-12 CN disclosed
CN-105462984-A NUCLEIC ACID FRAGMENT BINDING TO TARGET PROTEIN TAGCYX BIOTECHNOLOGIES 2016-04-06 CN disclosed
CN-103168235-B For analyzing the method for the existence of disease markers in experimenter's blood sample STICHTING VU-VUMC (NL) 2016-01-13 CN disclosed
CN-104703610-A Modulation of androgen receptor expression ISIS PHARMACEUTICALS INC 2015-06-10 CN disclosed
CN-102448992-B Stabilizing composition for immobilized biomolecules LEUKOCARE AG 2015-06-10 CN disclosed
CN-104284675-A Novel binding molecules with antitumor activity COVAGEN AG 2015-01-14 CN disclosed
EP-2419110-A1 METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES Enzon Pharmaceuticals, Inc. (US) 2012-02-22 EP disclosed
EP-2414520-A2 METHODS OF MODULATING AN IMMUNE RESPONSE TO A VIRAL INFECTION Altair Therapeutics, Inc. (US) 2012-02-08 EP disclosed
WO-2010120861-A1 METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES ENZON PHARMACEUTICALS, INC. (US) 2010-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146278-A1 Biological Substance Treatment Method, Reaction Detection Method, Biological Substance Treatment Apparatus, and Reaction Detection Apparatus TACR1, TACR2, TNF AKR1B1 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.