Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453125 | 1.00 | KDM4E (0.43) | KDM4ELMNAHCAR2HDAC3HDAC4 | |
| SCHEMBL20772854 | 0.82 | CCNC (0.38) | KDM4ELMNAPKM | |
| SCHEMBL5713386 | 0.78 | LMNA (0.33) | KDM4ELMNAATMHPGDMEN1 | |
| SCHEMBL17282984 | 0.74 | MMP2 (0.32) | MMP2MMP9 | |
| SCHEMBL5677189 | 0.73 | LMNA (0.59) | KDM4ELMNAHCAR2HDAC3HDAC4 | |
| SCHEMBL9349340 | 0.73 | CA1 (0.47) | KDM4ELMNAHCAR2HDAC3HDAC4 | |
| SCHEMBL17282612 | 0.72 | MTNR1A (0.34) | KDM4EMMP2GAAMAPTMMP9 | |
| Fumaric Acid SCHEMBL28259207 | 0.72 | TSHR (0.36) | KDM4ELMNAHCAR2HDAC3HDAC4 | |
| Maleic Acid SCHEMBL28260900 | 0.72 | TSHR (0.36) | KDM4ELMNAHCAR2HDAC3HDAC4 | |
| SCHEMBL18681680 | 0.71 | SMN1; SMN2 (0.30) | LMNAHSD17B10ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1237054-C | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2006-01-18 | — | — | CN | claimed |
| EP-1219173-B1 | INSECTICIDES AND ACARICIDES | AGRO KANESHO CO LTD (JP) | 2004-06-16 | — | — | EP | claimed |
| US-20030191171-A1 | Pyrazolyl compound | AGRO-KANESHO CO., LTD. (JP) | 2003-10-09 | — | — | US | claimed |
| CN-1399515-A | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2003-02-26 | — | — | CN | claimed |
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | AGRO-KANESHO CO., LTD. (JP) | 2002-10-24 | — | — | US | claimed |
| EP-1219173-A1 | INSECTICIDAL AND ACARICIDAL AGENTS | Agro-Kanesho Co., Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-0483851-B1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | MITSUBISHI CHEM CORP (JP) | 1996-03-13 | — | — | EP | claimed |
| EP-0433899-B1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | MITSUBISHI CHEM CORP (JP) | 1995-04-12 | — | — | EP | claimed |
| US-5128350-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-07 | — | — | US | claimed |
| EP-0483851-A1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | Mitsubishi Chemical Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| US-5055477-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES, USEFUL AS SYSTEMIC FUNGICIDES FOR PLANT AND MATERIAL PROTECTION | MITSUBISHI KASEI CORPORATION (JP) | 1991-10-08 | — | — | US | claimed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | claimed |
| EP-1781617-A4 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1781617-A2 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-09 | — | — | EP | disclosed |
| EP-0945437-B1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS BIOTECH CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| CN-1237054-C | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-5055477-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES, USEFUL AS SYSTEMIC FUNGICIDES FOR PLANT AND MATERIAL PROTECTION | MITSUBISHI KASEI CORPORATION (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433899-A1 | New pyrazolyl acrylic acid derivatives, useful as systemic fungicides for plant and material protection | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | GSTO1, CBR3, CBR1 | KDM4E 2776/4885LMNA 2648/4885HCAR2 2460/4885 |
| US-20030191171-A1 | Pyrazolyl compound | GSTO1, CBR3, GSTM1 | KDM4E 2533/4885LMNA 2609/4885HCAR2 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.