Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678203 | 0.84 | DAO (0.49) | EGLN1PTGS2PTGS1PIM1 | |
| SCHEMBL5677159 | 0.75 | DAO (0.59) | EGLN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23147745 | 0.74 | NUDT1 (0.44) | KDM4EHPGD | |
| SCHEMBL29721792 | 0.74 | NUDT1 (0.44) | KDM4EHPGD | |
| SCHEMBL31145982 | 0.73 | GRIN2D (0.41) | EGLN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5681251 | 0.73 | KDM4E (0.40) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5676880 | 0.72 | KDM4E (0.43) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL4066394 | 0.71 | PIM1 (0.50) | KMT2AKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL31145797 | 0.70 | GRIN2D (0.39) | EGLN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31146183 | 0.70 | GRIN2D (0.39) | EGLN1KMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6632919-B1 | Bind Watson-Crick base pairs in a double helix; specific for thymidine | Nielsen, Peter (DK) | 2003-10-14 | — | — | US | disclosed |