Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676978 | 0.82 | HRH4 (0.39) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL27840816 | 0.77 | KDM4E (0.49) | KDM4EKMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL5677159 | 0.77 | DAO (0.59) | KDM4EKMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5677293 | 0.72 | EGLN1 (0.40) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL4067945 | 0.72 | HSD17B10 (0.61) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL589427 | 0.71 | ALDH1A1 (0.56) | KDM4EKMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL19127026 | 0.71 | KDM4E (0.46) | KDM4EKMT2AADORA2AADORA1 | |
| SCHEMBL25232378 | 0.71 | PIN1 (0.49) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL30434363 | 0.69 | MAPK1 (0.61) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL5678790 | 0.69 | MAPK1 (0.61) | KDM4EKMT2AHSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6632919-B1 | Bind Watson-Crick base pairs in a double helix; specific for thymidine | Nielsen, Peter (DK) | 2003-10-14 | — | — | US | disclosed |