Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678200 | 0.88 | OPRM1 (0.79) | OPRM1OPRD1 | |
| SCHEMBL5680793 | 0.88 | OPRM1 (0.81) | OPRM1OPRD1 | |
| SCHEMBL5677457 | 0.87 | OPRM1 (0.80) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6310148 | 0.86 | OPRM1 (0.98) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6309667 | 0.86 | OPRM1 (0.98) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6309665 | 0.86 | OPRM1 (0.98) | OPRM1OPRD1 | |
| SCHEMBL6717020 | 0.81 | OPRM1 (0.74) | OPRM1OPRD1 | |
| SCHEMBL5679168 | 0.79 | OPRM1 (0.69) | OPRM1OPRD1 | |
| SCHEMBL5105118 | 0.79 | OPRM1 (0.65) | OPRM1OPRD1 | |
| SCHEMBL5679341 | 0.78 | OPRM1 (0.84) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615920-A1 | 3-BENZHYDRYLIDENE-8-AZA-BICYCLO [3.2.1] OCTANE DERIVATIVES WITH OPIOID RECEPTOR ACTIVITY | Pfizer Products Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040254190-A1 | 3-Benzhydrylidene-8-aza-bicyclo[3.2.1]octane derivatives with opioid receptor activity | PFIZER INC | 2004-12-16 | — | — | US | disclosed |
| WO-2004092165-A1 | 3-BENZHYDRYLIDENE-8-AZA-BICYCLO[3.2.1]OCTANE DERIVATIVES WITH OPIOID RECEPTOR ACTIVITY | PFIZER PRODUCTS INC. (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254190-A1 | 3-Benzhydrylidene-8-aza-bicyclo[3.2.1]octane derivatives with opioid receptor activity | OPRM1, OPRD1, OPRK1 | OPRM1 1/4885OPRD1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.