Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 16/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681661 | 0.86 | OPRM1 (0.79) | OPRM1OPRD1ABCB11KCNH2 | |
| SCHEMBL6311204 | 0.85 | OPRD1 (1.00) | OPRM1OPRD1 | |
| SCHEMBL6310090 | 0.85 | OPRD1 (1.00) | OPRM1OPRD1 | |
| SCHEMBL6310094 | 0.85 | OPRD1 (1.00) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6310068 | 0.84 | OPRD1 (0.97) | OPRM1OPRD1 | |
| SCHEMBL4927224 | 0.82 | OPRD1 (1.00) | OPRM1OPRD1ABCB11KCNH2 | |
| SCHEMBL5678200 | 0.81 | OPRM1 (0.79) | OPRM1OPRD1 | |
| SCHEMBL5677362 | 0.81 | OPRM1 (0.78) | OPRM1OPRD1 | |
| Fumaric Acid SCHEMBL6309238 | 0.81 | OPRD1 (0.89) | OPRM1OPRD1 | |
| Fumaric Acid SCHEMBL6309233 | 0.81 | OPRD1 (0.89) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254190-A1 | 3-Benzhydrylidene-8-aza-bicyclo[3.2.1]octane derivatives with opioid receptor activity | PFIZER INC | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254190-A1 | 3-Benzhydrylidene-8-aza-bicyclo[3.2.1]octane derivatives with opioid receptor activity | OPRM1, OPRD1, OPRK1 | OPRM1 1/4885OPRD1 2/4885ABCB11 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.