Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.88 |
| ▸ | CA1 | P00915 | 10/20 | 0.85 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678390 | 0.94 | CA2 (1.00) | CA2CA1EPHX2NR1H4CA12 | |
| SCHEMBL6280545 | 0.86 | CA2 (0.88) | CA2CA1EPHX2NR1H4CA12 | |
| SCHEMBL678923 | 0.85 | CA2 (0.85) | CA2CA1EPHX2NR1H4CA12 | |
| SCHEMBL6046379 | 0.85 | MEN1 (0.90) | CA2CA1KMT2ACA12CA5A | |
| SCHEMBL13379248 | 0.85 | CA2 (0.85) | CA2CA1EPHX2NR1H4KMT2A | |
| SCHEMBL6237833 | 0.85 | CA2 (0.67) | CA2CA1EPHX2NR1H4KMT2A | |
| SCHEMBL933464 | 0.84 | ALDH1A1 (0.72) | CA2CA1EPHX2NR1H4CA12 | |
| SCHEMBL4636418 | 0.84 | HPGDS (0.73) | CA2CA1EPHX2NR1H4KMT2A | |
| SCHEMBL16127900 | 0.84 | APEX1 (0.74) | CA2CA1KMT2ACA12CA5A | |
| SCHEMBL11807861 | 0.84 | MEN1 (0.87) | CA2CA1KMT2ACA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633714-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004108675-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | claimed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | claimed |
| US-7019033-B2 | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives | WARNER-LAMBERT COMPANY (US) | 2006-03-28 | — | — | US | disclosed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |