SCHEMBL5679019

SCHEMBL5679019

O=C1N=NC(S(=O)(=O)O)=C1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
P2RX7 Q99572 1/20 0.38
PDE4B Q07343 1/20 0.37
FGFR1 P11362 2/20 0.37
FGFR2 P21802 2/20 0.37
FGFR4 P22455 2/20 0.37
FGFR3 P22607 2/20 0.37
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
SRC P12931 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
PTGS2 P35354 4/20 0.35
PTGS1 P23219 1/20 0.35
ALDH1A1 P00352 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL11041536 0.91 PTPN1 (0.36) SMN1; SMN2TSHRP2RX7CYP2D6PTGS2
SCHEMBL11063320 0.83 AKR1C1 (0.33) SMN1; SMN2PDE4BPTGS2ALDH1A1NPSR1
SCHEMBL11042655 0.81 TRPA1 (0.35) RCE1
SCHEMBL7761880 0.70 TSHR (0.39) SMN1; SMN2TSHRP2RX7FGFR1FGFR2
SCHEMBL11515589 0.70 TSHR (0.40) SMN1; SMN2TSHRPOLBCYP2D6PTGS2
SCHEMBL11573340 0.70 CYP2C9 (0.42) SMN1; SMN2TSHRPTGS2ALDH1A1LMNA
SCHEMBL10359088 0.70 PDE4B (0.39) P2RX7PDE4BFGFR1FGFR2FGFR4
SCHEMBL182947 0.68 PDE4B (0.42) P2RX7PDE4BPOLBHSP90AA1HSP90AB1
SCHEMBL7463139 0.68 PDE4B (0.38) SMN1; SMN2P2RX7PDE4BFGFR1FGFR2
SCHEMBL5232817 0.68 P2RX7 (0.35) TSHRP2RX7PDE4BFGFR1FGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105646356-B A kind of preparation method of sulfophenyl pyrazolone and its intermediate Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2018-08-31 CN claimed
CN-105646356-A Preparation method of sulfophenyl pyrazolone and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-06-08 CN claimed
WO-2025109600-A1 PROCESS FOR PREPARATION OF SULFONYL PYRAZOLONES ADAMA AGAN LTD. (IL) 2025-05-30 WO disclosed
CN-105646356-B A kind of preparation method of sulfophenyl pyrazolone and its intermediate Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2018-08-31 CN disclosed
CN-105646356-B A kind of preparation method of sulfophenyl pyrazolone and its intermediate Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2018-08-31 CN disclosed
CN-105646356-A Preparation method of sulfophenyl pyrazolone and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-06-08 CN disclosed
CN-105646356-A Preparation method of sulfophenyl pyrazolone and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-06-08 CN disclosed
CN-105646356-A Preparation method of sulfophenyl pyrazolone and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-06-08 CN disclosed
US-7132516-B2 Mono-or bisazo copper complex dyestuffs CLARIANT FINANCE (BVI) LIMITED (VG) 2006-11-07 US disclosed
EP-1472317-B1 MONO- OR BISAZO COPPER COMPLEX DYESTUFFS CLARIANT FINANCE BVI LTD (VG) 2006-03-22 EP disclosed
US-20050020822-A1 Mono-or bisazo copper complex dyestuffs CLARIANT FINANCE (BVI) LIMITED (VG) 2005-01-27 US disclosed
EP-1472317-A1 MONO- OR BISAZO COPPER COMPLEX DYESTUFFS Clariant International Ltd. (CH) 2004-11-03 EP disclosed
WO-2003064537-A1 MONO- OR BISAZO COPPER COMPLEX DYESTUFFS CLARIANT INTERNATIONAL LTD (CH) 2003-08-07 WO disclosed
US-5352729-A Containing a monoethylenically unsaturated dicarboxylic acid or anhydride that may be modifed with ammonia, amines, alcohols, amino- or hydroxycarboxylic acids, or alkali metal hydroxides BASF AKTIENGESELLSCHAFT (DE) 1994-10-04 US disclosed
US-4490151-A Disazo sulfophenylpyrazolonestilbene dyes and direct dyes to color cellulose black CROMPTON AND KNOWLES CORPORATION (US) 1984-12-25 US disclosed
US-4455258-A Disazo sulfophenylpyrazolone-sulfostilbene dyes CROMPTON AND KNOWLES CORPORATION (US) 1984-06-19 US disclosed
US-4150020-A MONOAZO DYES BURLINGTON INDUSTRIES, INC. (US) 1979-04-17 US disclosed
US-4134722-A Reactive dyeing system using phosphorus acid dyes with a cyanamide compound BURLINGTON INDUSTRIES, INC. (US) 1979-01-16 US disclosed