Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679019 | 0.91 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL11042655 | 0.90 | TRPA1 (0.35) | PTPN1PTPN6MAPK1TDP1 | |
| SCHEMBL11063320 | 0.84 | AKR1C1 (0.33) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| (Z)-1,2-Diphenylethene SCHEMBL8520705 | 0.70 | LMNA (0.54) | MAPK1LMNASMN1; SMN2ALDH1A1MAPT | |
| (Z)-1,2-Diphenylethene SCHEMBL8520704 | 0.70 | LMNA (0.54) | MAPK1LMNASMN1; SMN2ALDH1A1MAPT | |
| (Z)-1,2-Diphenylethene SCHEMBL28205397 | 0.66 | MAOB (0.52) | PTPN1MAPK1LMNASMN1; SMN2ALDH1A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL27449534 | 0.66 | PTPN1 (0.47) | PTPN1PTPN6LMNASMN1; SMN2KDM4E | |
| SCHEMBL7463139 | 0.65 | PDE4B (0.38) | LMNASMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL28748742 | 0.65 | TSHR (0.62) | PTPN1LMNASMN1; SMN2ALDH1A1MAPT | |
| Biphenyl SCHEMBL11585431 | 0.64 | PPARG (0.48) | LMNASMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490151-A | Disazo sulfophenylpyrazolonestilbene dyes and direct dyes to color cellulose black | CROMPTON AND KNOWLES CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-4455258-A | Disazo sulfophenylpyrazolone-sulfostilbene dyes | CROMPTON AND KNOWLES CORPORATION (US) | 1984-06-19 | — | — | US | disclosed |