SCHEMBL7761880

SCHEMBL7761880

O=C1N=NC(c2ccccc2)=C1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HDAC6 Q9UBN7 1/20 0.36
POLB P06746 2/20 0.35
CYP2D6 P10635 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
MMP2 P08253 2/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
BACE1 P56817 1/20 0.31
RCE1 Q9Y256 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515589 0.74 TSHR (0.40) TSHRSMN1; SMN2HDAC6POLBCYP2D6
SCHEMBL5679019 0.70 SMN1; SMN2 (0.39) TSHRSMN1; SMN2HDAC6POLBCYP2D6
SCHEMBL10359088 0.70 PDE4B (0.39) ALDH1A1LMNAMAPTHTTP2RX7
SCHEMBL11519983 0.69 FGFR1 (0.43) TSHRSMN1; SMN2ALDH1A1LMNAKDM4E
SCHEMBL10964297 0.68 LMNA (0.36) ALDH1A1BACE1LMNAMAPTHTT
SCHEMBL10688416 0.68 MAPT (0.36) SMN1; SMN2POLBALDH1A1LMNAMAPT
SCHEMBL214204 0.68 L3MBTL1 (0.36) TSHRPOLBL3MBTL1ALDH1A1LMNA
Biphenyl SCHEMBL7077316 0.65 ALDH1A1 (0.60) TSHRSMN1; SMN2ALDH1A1CA1CA2
Biphenyl SCHEMBL1681197 0.65 ALDH1A1 (0.60) TSHRSMN1; SMN2ALDH1A1CA1CA2
SCHEMBL28035650 0.64 KIF11 (0.38) TSHRHDAC6POLBL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542033-B2 Use of pigment preparations for the manufacture of pastes, printing inks and paints BASF AG (DE) 2001-04-25 EP disclosed
EP-0542033-B1 Use of pigment preparations for the manufacture of pastes, printing inks and paints BASF AG (DE) 1997-01-15 EP disclosed
US-5352729-A Containing a monoethylenically unsaturated dicarboxylic acid or anhydride that may be modifed with ammonia, amines, alcohols, amino- or hydroxycarboxylic acids, or alkali metal hydroxides BASF AKTIENGESELLSCHAFT (DE) 1994-10-04 US disclosed
EP-0542033-A2 Use of pigment preparations for the manufacture of pastes, printing inks and paints BASF Aktiengesellschaft (DE) 1993-05-19 EP disclosed
US-4256896-A THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES CIBA-GEIGY AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4246410-A BENZINDOLE DYES OF YELLOW AND RED CIBA -GEIGY AKTIENGESELLSCHAFT (CH) 1981-01-20 US disclosed
US-4246422-A Naphtholactam dyestuffs CIBA-GEIGY AG (CH) 1981-01-20 US disclosed
US-4236007-A YELLOW SHADES ON POLYESTERS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-25 US disclosed
US-4180665-A Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-25 US disclosed
US-4159379-A Dispersion dyestuffs of the naphtholactam series CIBA-GEIGY AG (CH) 1979-06-26 US disclosed
US-4148805-A POLYESTERS, RED, YELLLOW CIBA-GEIGY AG (CH) 1979-04-10 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed