SCHEMBL5679198

SCHEMBL5679198

Nc1ccc(S(=O)(=O)CC(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.63
MMP7 P09237 1/20 0.63
MMP14 P50281 1/20 0.63
GAA P10253 1/20 0.55
TSHR P16473 4/20 0.50
ALDH1A1 P00352 2/20 0.50
NT5E P21589 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
DHFR P00374 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 1/20 0.48
MPO P05164 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
HTR6 P50406 1/20 0.48
CA12 O43570 1/20 0.46
USP2 O75604 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3479371 0.83 ALDH1A1 (0.69) MMP2MMP7MMP14GAATSHR
SCHEMBL5247509 0.82 ALDH1A1 (0.67) MMP2MMP7MMP14GAATSHR
SCHEMBL1981537 0.81 MMP2 (0.66) MMP2MMP7MMP14LMNACA2
SCHEMBL270706 0.80 MMP2 (0.77) MMP2MMP7MMP14ALDH1A1SMN1; SMN2
SCHEMBL7874006 0.80 HTT (0.62) GAATSHRALDH1A1NT5ETDP1
SCHEMBL7900689 0.79 MMP2 (0.63) MMP2MMP7MMP14
SCHEMBL10803103 0.79 MMP2 (0.63) MMP2MMP7MMP14TSHRALDH1A1
SCHEMBL10203496 0.79 MMP2 (0.63) MMP2MMP7MMP14LMNACA1
SCHEMBL924405 0.79 ALDH1A1 (0.69) MMP2MMP7MMP14ALDH1A1LMNA
SCHEMBL3289731 0.79 MMP2 (0.63) MMP2MMP7MMP14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116622253-B Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2024-04-12 CN claimed
CN-116622253-A Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2023-08-22 CN claimed
CN-116622253-B Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2024-04-12 CN disclosed
CN-116622253-B Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2024-04-12 CN disclosed
CN-116622253-A Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2023-08-22 CN disclosed
CN-116622253-A Disperse dye composition and preparation method and application thereof 临沂市东裕新材料科技有限公司 2023-08-22 CN disclosed
WO-2022056447-A1 CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE GENZYME CORPORATION (US) 2022-03-17 WO disclosed
CN-111019393-B Yellow liquid dye composition for dyeing and printing and application thereof 沈阳化工研究院有限公司 2022-02-11 CN disclosed
CN-111019393-A Yellow liquid dye composition for dyeing and printing and application thereof 沈阳化工研究院有限公司 2020-04-17 CN disclosed
EP-2986625-B1 MIXED MODE LIGANDS BIO RAD LABORATORIES (US) 2020-03-11 EP disclosed
US-10583429-B2 Mixed mode ligands BIO-RAD LABORATORIES, INC. (US) 2020-03-10 US disclosed
US-20170247320-A1 NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF CJ HEALTHCARE CORPORATION (KR) 2017-08-31 US disclosed
EP-3187488-A1 NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF CJ Healthcare Corporation (KR) 2017-07-05 EP disclosed
US-20150258539-A1 MIXED MODE LIGANDS BIO RAD LABORATORIES (US) 2015-09-17 US disclosed
US-20150258539-A1 MIXED MODE LIGANDS BIO RAD LABORATORIES (US) 2015-09-17 US disclosed
US-20150258539-A1 MIXED MODE LIGANDS BIO RAD LABORATORIES (US) 2015-09-17 US disclosed
US-7029835-B2 Photothermographic element comprising improved base precursors and methods for their use EASTMAN KODAK COMPANY (US) 2006-04-18 US disclosed
US-20040185352-A1 Photothermographic element comprising improved base precursors and methods for their use CARESTREAM HEALTH, INC. 2004-09-23 US disclosed
EP-1422553-A1 Improved base precursors for use in a photothermographic element EASTMAN KODAK COMPANY (US) 2004-05-26 EP disclosed
US-6699651-B1 THERMALLY BLEACHABLE FILTER DYE COMPOSITIONS COMPRISING A BASE PRECURSOR THAT IS THE SALT OF AN ORGANIC BASE WITH AN ARYLSULFONYLACETIC ACID EASTMAN KODAK COMPANY 2004-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150258539-A1 MIXED MODE LIGANDS MRPL21, FABP2, MYOF MMP2 2876/4885MMP7 2585/4885MMP14 3311/4885
US-20170247320-A1 NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF SLC5A2, SLC5A1, IAPP MMP2 3693/4885MMP7 1793/4885MMP14 2940/4885
US-10583429-B2 Mixed mode ligands MRPL21, CD2BP2, FABP1 MMP2 982/4885MMP7 1264/4885MMP14 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.