Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.63 |
| ▸ | MMP7 | P09237 | 3/20 | 0.63 |
| ▸ | MMP14 | P50281 | 2/20 | 0.63 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639234 | 0.82 | MMP2 (0.49) | MMP2MMP7MMP14PLCG1MMP1 | |
| SCHEMBL22333253 | 0.82 | ALDH1A1 (0.67) | MMP2PLCG1MMP1MMP9MMP13 | |
| SCHEMBL29087444 | 0.82 | PLCG1 (0.57) | MMP2MMP7MMP14PLCG1MMP1 | |
| SCHEMBL1981537 | 0.81 | MMP2 (0.66) | MMP2MMP7MMP14HSD11B1FFAR1 | |
| SCHEMBL270706 | 0.80 | MMP2 (0.77) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL947975 | 0.80 | HSD11B1 (0.63) | PLCG1HSD11B1KMT2A | |
| SCHEMBL28543793 | 0.80 | RECQL (0.71) | MMP2MMP7MMP14PLCG1HSD11B1 | |
| SCHEMBL3289731 | 0.79 | MMP2 (0.63) | MMP2MMP7MMP14HSD11B1FFAR1 | |
| SCHEMBL5679198 | 0.79 | MMP2 (0.63) | MMP2MMP7MMP14 | |
| SCHEMBL10203496 | 0.79 | MMP2 (0.63) | MMP2MMP7MMP14HSD11B1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197791-B1 | ANTIARTHRITIC AGENTS; WOUND HEALING AGENTS; ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY | 2001-03-06 | — | — | US | disclosed |
| US-4626500-A | N-HETEROCYCIC CARBOXYLIC ACID | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-02 | — | — | US | disclosed |