Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716894 | 0.88 | AMY1A (0.44) | KMT2AMEN1MYCTSHRCYP2C19 | |
| SCHEMBL14991279 | 0.88 | AMY1A (0.44) | KMT2AMEN1MYCTSHRCYP2C19 | |
| SCHEMBL909723 | 0.86 | MEN1 (0.46) | KMT2AMEN1MYCCYP3A4CYP2D6 | |
| SCHEMBL29664944 | 0.85 | MEN1 (0.40) | KMT2AMEN1CNR2CYP2D6ALDH1A1 | |
| SCHEMBL5676910 | 0.85 | LMNA (0.40) | KMT2AMEN1MYCCNR2RAB9A | |
| SCHEMBL21066919 | 0.83 | PTGER1 (0.44) | KMT2AMEN1MYCTSHRRAPGEF4 | |
| SCHEMBL1180196 | 0.81 | GAA (0.41) | KMT2AMEN1MYCTSHRRAPGEF4 | |
| SCHEMBL30823619 | 0.81 | GAA (0.41) | KMT2AMEN1MYCTSHRRAPGEF4 | |
| SCHEMBL196533 | 0.80 | ACHE (0.46) | KMT2AMEN1CYP3A4TSHRNPC1 | |
| SCHEMBL1228376 | 0.80 | ACHE (0.46) | KMT2AMEN1CYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229016-B1 | Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour | DEGUSSA (DE) | 2006-01-11 | — | — | EP | disclosed |
| EP-1229016-A2 | Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour | Degussa AG (DE) | 2002-08-07 | — | — | EP | disclosed |