Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5679940 | 0.95 | CA12 (0.39) | ALDH1A1CYP1A2CA12CA1CA2 | |
| Sulfuric Acid SCHEMBL5679930 | 0.92 | CA12 (0.41) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL8974916 | 0.92 | NQO1 (0.44) | ALDH1A1CYP1A2FFAR1FFAR4MAPT | |
| Hydrochloric Acid SCHEMBL3805858 | 0.90 | NQO1 (0.42) | ALDH1A1CYP1A2FFAR1FFAR4MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL11061865 | 0.88 | PTGS2 (0.40) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL8988230 | 0.82 | ADORA3 (0.41) | ALDH1A1MAPTKDM4ELMNAHTT | |
| SCHEMBL11067113 | 0.79 | KMT2A (0.52) | ALDH1A1CYP1A2MAPTKDM4ELMNA | |
| Sulfuric Acid SCHEMBL5676621 | 0.74 | LTA4H (0.41) | ALDH1A1LMNATSHRNPSR1GAA | |
| SCHEMBL10784333 | 0.73 | BACE1 (0.42) | MAPTLMNATSHRHTTGAA | |
| SCHEMBL14588712 | 0.72 | KDM4E (0.47) | ALDH1A1CYP1A2CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656551-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | Honeywell International Inc. (US) | 2006-05-17 | — | — | EP | claimed |
| WO-2005019816-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | HONEYWELL INTERNATIONAL, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| US-20050042758-A1 | Leak detection method using microencapsulated dye precursor | HONEYWELL CORPORATION | 2005-02-24 | — | — | US | claimed |
| US-4021243-A | Diazo light-sensitive copying composition and process of using in the manufacture of screen printing stencils | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | claimed |
| EP-1421447-A4 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | KODAK POLYCHROME GRAPHICS LLC (US) | 2006-09-06 | — | — | EP | disclosed |
| US-7056639-B2 | Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid | EASTMAN KODAK COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1656551-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | Honeywell International Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| US-6921620-B2 | Acid curable composition of an acid generator; an infrared absorber; and optional colorant | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-07-26 | — | — | US | disclosed |
| US-20050079439-A1 | Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-04-14 | — | — | US | disclosed |
| WO-2005019816-A1 | LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR | HONEYWELL INTERNATIONAL, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050042758-A1 | Leak detection method using microencapsulated dye precursor | HONEYWELL CORPORATION | 2005-02-24 | — | — | US | disclosed |
| US-6821583-B2 | SUBSTRATE WITH A CROSSLINKED LAYER DISPOSED ON IT HAVING AN IMAGEABLE INK-RECEPTIVE LAYER THAT IS ABLATION FREE | KODAK POLYCHROME GRAPHICS LLC | 2004-11-23 | — | — | US | disclosed |
| US-6783911-B2 | POSITIVE WORKING; HYDROXYFUNCTIONAL RESIN COMPRISING A COVALENTLY BOUND RADIATION SENSITIVE GROUP CAPABLE OF INCREASING THE SOLUBILITY OF SAID IMAGEABLE COMPOSITION IN AN ALKALINE DEVELOPER UPON EXPOSURE TO RADIATION | KODAK POLYCHROME GRAPHICS LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1421447-A1 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | Kodak Polychrome Graphics LLC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040009363-A1 | Substrate with a crosslinked layer disposed on it having an imageable ink-receptive layer that is ablation free | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2004-01-15 | — | — | US | disclosed |
| US-20030194635-A1 | Isocyanate crosslinked imageable compositions | KODAK POLYCHROME GRAPHICS, L.L.C. | 2003-10-16 | — | — | US | disclosed |
| US-20030129526-A1 | Containing acid curable polymer, acid generator and infrared radiation absorberr | KODAK POLYCHROME GRAPHICS, L.L.C. | 2003-07-10 | — | — | US | disclosed |
| US-20030113655-A1 | Acid curable composition of an acid generator; an infrared absorber; and optional colorant | KODAK POLYCHROME GRAPHICS, L.L.C | 2003-06-19 | — | — | US | disclosed |
| WO-2003019294-A1 | IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID | KODAK POLYCHROME GRAPHICS, L.L.C. (US) | 2003-03-06 | — | — | WO | disclosed |
| US-4021243-A | Diazo light-sensitive copying composition and process of using in the manufacture of screen printing stencils | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |