Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609540 | 0.76 | HTR2A (0.42) | GRIN2BSIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL3091289 | 0.70 | NR1H2 (0.43) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL3948798 | 0.69 | MAPK1 (0.37) | — | |
| SCHEMBL8120599 | 0.68 | NOS1 (0.39) | DDB1CRBNNOS3NOS1NOS2 | |
| SCHEMBL9403738 | 0.67 | CYP19A1 (0.49) | — | |
| SCHEMBL7154324 | 0.64 | MAOB (0.50) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL3409878 | 0.64 | ESR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL14691904 | 0.64 | MAOA (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL20874433 | 0.63 | NR3C1 (0.74) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL11750905 | 0.62 | SRD5A1 (0.40) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7011765-B2 | Heat transfer fluid based on polyphenylmethanes exhibiting improved thermal stability | ARKEMA (FR) | 2006-03-14 | — | — | US | disclosed |
| EP-1268705-B1 | HEAT TRANSFER FLUID BASED ON POLYPHENYLMETHANES EXHIBITING IMPROVED THERMAL STABILITY | ARKEMA (FR) | 2006-02-15 | — | — | EP | disclosed |
| CN-1200989-C | Heat transfer fuid based on polyphenylmethanes exhibiting improved thermal stability | ATOFINA (FR) | 2005-05-11 | — | — | CN | disclosed |
| US-20040031949-A1 | Heat transfer fluid based on polyphenylmethanes exhibiting improved thermal stability | ATOFINA (FR) | 2004-02-19 | — | — | US | disclosed |
| CN-1432054-A | Heat transfer fuid based on polyphenylmethanes exhibiting improved thermal stability | ATOFINA (FR) | 2003-07-23 | — | — | CN | disclosed |