SCHEMBL5680245

SCHEMBL5680245

[CH2]CCC1CCC(COC(C)=O)CC1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
TYK2 P29597 1/20 0.34
JAK3 P52333 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NLRP3 Q96P20 2/20 0.33
SLC1A3 P43003 2/20 0.31
SLC1A2 P43004 2/20 0.31
SLC1A1 P43005 2/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
PDK1 Q15118 1/20 0.30
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682484 0.91 JAK2 (0.33) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL6256094 0.87
SCHEMBL5696892 0.87 ALDH1A1 (0.43) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL17029138 0.87 ALDH1A1 (0.43) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL5682345 0.86 ALDH1A1 (0.36) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL929455 0.83 ALDH1A1 (0.37) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL5680467 0.82 LMNA (0.34) ALDH1A1LMNAHSD17B10NLRP3
SCHEMBL23675572 0.82 ALDH1A1 (0.36) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL31640166 0.81 LMNA (0.47) ALDH1A1LMNAJAK2JAK1TYK2
SCHEMBL20087550 0.79 PKM (0.44) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1184396-B1 (Meth)acrylate ester-based resin composition NIPPON CATALYTIC CHEM IND (JP) 2006-02-01 EP disclosed
US-6686413-B2 AQUEOUS DISPERSON OF A POLYMER CONTAINING UNITS OF A CYCLOHEXYLALKYL ESTER OF (METH)ACRYLIC ACID NIPPON SHOKUBAI CO., LTD. (JP) 2004-02-03 US disclosed
US-6489396-B2 A CYCLOHEXYL CONTAINING (METH)ACRYLIC ESTER-BASED POLYMER CROSSLINKED WITH A DI-FUNCTIONAL CROSSLINKING AGENT; LOW VISCOSITY RESIN FOR LOW VOLATILE ORGANIC COMPOUND (VOC)-PAINTS NIPPON SHOKUBAI CO., LTD. (JP) 2002-12-03 US disclosed
US-20020091197-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-07-11 US disclosed
EP-1205498-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-05-15 EP disclosed
US-20020045702-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-18 US disclosed
EP-1184396-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045702-A1 (Meth)acrylate ester-based resin composition MNAT1, MAT1A, COPE ALDH1A1 298/4885LMNA 1220/4885JAK2 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.