SCHEMBL5680376

SCHEMBL5680376

Cc1cccc(Nc2cccc3c2C(=O)OC32c3ccccc3Oc3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
NPSR1 Q6W5P4 2/20 0.40
PRKCB P05771 1/20 0.38
ADORA2A P29274 1/20 0.37
P2RY2 P41231 1/20 0.36
P2RY4 P51582 1/20 0.36
P2RY6 Q15077 1/20 0.36
P2RY12 Q9H244 1/20 0.36
MAPT P10636 5/20 0.36
HPGD P15428 3/20 0.36
HTT P42858 3/20 0.36
FTO Q9C0B1 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
PRMT1 Q99873 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6856340 0.88 NPC1 (0.44) LMNANPSR1PRKCBP2RY2P2RY4
SCHEMBL3346303 0.87 ALDH1A1 (0.40) LMNANPSR1PRKCBMAPTHPGD
SCHEMBL387083 0.87 NPSR1 (0.38) LMNANPSR1PRKCBADORA2AP2RY2
SCHEMBL9679820 0.86 HTT (0.41) LMNAHTTTDP1MEN1KMT2A
SCHEMBL6535406 0.85 NPSR1 (0.38) LMNANPSR1PRKCBADORA2AP2RY2
SCHEMBL10387982 0.85 ALDH1A1 (0.38) LMNANPSR1PRKCBMAPTHPGD
SCHEMBL5685570 0.85 LMNA (0.42) LMNANPSR1P2RY2P2RY4MAPT
SCHEMBL387762 0.85 PRKCB (0.36) LMNANPSR1PRKCBADORA2AP2RY2
SCHEMBL9643669 0.83 RAPGEF4 (0.43) LMNANPSR1MAPTHPGDHTT
SCHEMBL10590866 0.83 ALDH1A1 (0.36) LMNAPRKCBMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP claimed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP claimed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO claimed
EP-1622858-A2 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2006-02-08 EP disclosed
WO-2004099116-A2 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed