Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896960 | 0.92 | HRH4 (0.47) | HRH4ALOX15MAPTNPC1RAB9A | |
| SCHEMBL5896947 | 0.90 | ALOX15 (0.47) | HRH4ALOX15MAPTNPC1RAB9A | |
| SCHEMBL5896819 | 0.83 | HRH4 (0.45) | HRH4ALOX15MAPTNPC1RAB9A | |
| SCHEMBL7365267 | 0.81 | HRH4 (0.55) | HRH4ALOX15MAPTNPC1RAB9A | |
| SCHEMBL17140836 | 0.80 | MTNR1A (0.47) | HRH4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5896864 | 0.77 | LEF1 (0.51) | HRH4MAPTNPC1RAB9ABRD4 | |
| SCHEMBL3029155 | 0.74 | HRH4 (0.58) | HRH4ALOX15MAPTSMN1; SMN2MEN1 | |
| SCHEMBL20287498 | 0.73 | ALOX15 (0.49) | HRH4ALOX15NPC1RAB9AHTR2C | |
| SCHEMBL5677239 | 0.73 | ALOX15 (0.49) | HRH4ALOX15NPC1RAB9ABRD4 | |
| SCHEMBL15584613 | 0.73 | KCNJ1 (0.57) | MAPTSMN1; SMN2BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |