Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896947 | 0.96 | ALOX15 (0.47) | HRH4ALOX15BRD4NPC1RAB9A | |
| SCHEMBL5680583 | 0.92 | HRH4 (0.47) | HRH4ALOX15BRD4NPC1RAB9A | |
| SCHEMBL5896819 | 0.90 | HRH4 (0.45) | HRH4ALOX15BRD4NPC1RAB9A | |
| SCHEMBL5896864 | 0.85 | LEF1 (0.51) | HRH4BRD4NPC1RAB9AMAPT | |
| SCHEMBL17140836 | 0.84 | MTNR1A (0.47) | HRH4BRD4NPC1RAB9ABCHE | |
| SCHEMBL5677239 | 0.82 | ALOX15 (0.49) | HRH4ALOX15BRD4NPC1RAB9A | |
| SCHEMBL20287498 | 0.82 | ALOX15 (0.49) | HRH4ALOX15NPC1RAB9ABCHE | |
| SCHEMBL20287482 | 0.81 | DRD2 (0.63) | HRH4BCHEALDH1A1DRD2DRD3 | |
| SCHEMBL7365267 | 0.81 | HRH4 (0.55) | HRH4ALOX15NPC1RAB9AMAPT | |
| SCHEMBL20289680 | 0.78 | ALOX15 (0.51) | ALOX15NPC1RAB9AALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | HRH4 1972/4885ALOX15 3366/4885BRD4 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.