Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | CTSG | P08311 | 1/20 | 0.62 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.62 |
| ▸ | CMA1 | P23946 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20684933 | 0.87 | HDAC1 (0.75) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24653262 | 0.87 | HDAC1 (0.75) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15296608 | 0.84 | POLB (0.62) | LMNAPOLBSMN1; SMN2GAANPC1 | |
| SCHEMBL6385721 | 0.84 | HDAC6 (0.76) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL19392502 | 0.83 | NAAA (0.58) | SMN1; SMN2NAAAHDAC3HDAC1HDAC2 | |
| SCHEMBL10708907 | 0.81 | PRSS1 (0.66) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL10154034 | 0.81 | GPR139 (0.61) | LMNAPOLBSMN1; SMN2NAAAHDAC4 | |
| SCHEMBL15296714 | 0.81 | PLK1 (0.64) | LMNASMN1; SMN2HDAC3HDAC1HDAC2 | |
| Betamipron SCHEMBL4498475 | 0.81 | PRSS1 (0.70) | PRSS1CTSGCTRB1CMA1LMNA | |
| Betamipron SCHEMBL605899 | 0.81 | PRSS1 (0.70) | PRSS1CTSGCTRB1CMA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633347-A1 | 2-PYRROLIDONE DERIVATIVES AND USE THEREOF AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004110434-A1 | 2-PYRROLIDONE DERIVATIVES AND USE THEREOF AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | claimed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |