Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681122 | 0.81 | FABP6 (0.47) | HTR3EHTR3BHTR3ABACE1HTR3D | |
| SCHEMBL11669082 | 0.81 | FABP6 (0.43) | HTR3EHTR3BHTR3ABACE1HTR3D | |
| SCHEMBL7045022 | 0.79 | CYP1A2 (0.40) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL8872830 | 0.76 | ALDH1A1 (0.39) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL8186343 | 0.76 | HTR3E (0.43) | HTR3EHTR3BHTR3ABACE1HTR3D | |
| SCHEMBL7044508 | 0.76 | CYP1A2 (0.38) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL16134549 | 0.76 | CYP1A2 (0.38) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL9505765 | 0.76 | HTT (0.52) | TYMSCYP1A2ALDH1A1KDM4EGRIN2D | |
| SCHEMBL20863650 | 0.73 | KDM4E (0.42) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL15844358 | 0.73 | RAD52 (0.43) | CYP1A2ALDH1A1KDM4EGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089316-A1 | Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof | BROWN TRUMAN R | 2006-04-27 | — | — | US | disclosed |
| US-5326779-A | Method of inhibiting the advanced glycosylation of proteins using 1,2-disubstituted-benzimidazoles | THE ROCKEFELLER UNIVERSITY (US) | 1994-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089316-A1 | Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof | ALDOA, FBP1, GYS2 | HTR3E 1624/4885HTR3B 1148/4885HTR3A 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.