Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679812 | 0.80 | MEN1 (0.51) | PDE3BPDE3A | |
| SCHEMBL3699142 | 0.75 | CYP1A2 (0.43) | PIM1PIM2RIPK2CSF1R | |
| SCHEMBL5679513 | 0.74 | DYRK1A (0.46) | DYRK1ADYRK1BTRPC5LPAR2 | |
| SCHEMBL5679762 | 0.73 | RAB9A (0.45) | DYRK1ADYRK1BLPAR2 | |
| SCHEMBL5679676 | 0.73 | RIPK1 (0.46) | DYRK1ADYRK1BLPAR2 | |
| SCHEMBL14521682 | 0.70 | RAB9A (0.63) | DYRK1ADYRK1B | |
| SCHEMBL15246748 | 0.70 | DYRK1A (0.49) | DYRK1ADYRK1BLPAR2 | |
| SCHEMBL32680214 | 0.70 | DYRK1A (0.49) | DYRK1ADYRK1BLPAR2 | |
| SCHEMBL5681358 | 0.70 | DYRK1A (0.49) | DYRK1ADYRK1BLPAR2 | |
| SCHEMBL21035092 | 0.69 | IDO1 (0.57) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |