Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681878 | 0.75 | PDE3B (0.40) | RIPK2PIM1PIM2CSF1R | |
| SCHEMBL5096961 | 0.74 | RAB9A (0.52) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL9892138 | 0.72 | CNR2 (0.62) | RAB9AHRH4CNR2 | |
| SCHEMBL5100530 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL27203390 | 0.71 | CACNA1G (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL29770413 | 0.71 | CACNA1G (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL13804780 | 0.70 | CACNA1H (0.51) | PIM1PIM2KDRCCNT1CDK9 | |
| SCHEMBL15288558 | 0.69 | BRD4 (0.35) | RAB9ARIPK2PIM1SLC2A1 | |
| SCHEMBL16342365 | 0.69 | RAB9A (0.45) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL4151151 | 0.69 | HRH4 (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077836-A2 | PYRROLIDINE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-08 | — | — | WO | disclosed |