Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4069903 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTTHRBHTTNPSR1 | |
| SCHEMBL5678330 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTTHRBHTTNPSR1 | |
| SCHEMBL7565959 | 0.86 | MAPT (0.41) | ALDH1A1MAPTTHRBHTTNPSR1 | |
| SCHEMBL2026167 | 0.84 | PTGS2 (0.37) | ALDH1A1KMT2AKDM4EGAATSHR | |
| SCHEMBL5680629 | 0.82 | MAPT (0.38) | ALDH1A1MAPTTHRBHTTNPSR1 | |
| SCHEMBL17485156 | 0.82 | SLC9A1 (0.36) | HTTTP53 | |
| SCHEMBL547467 | 0.82 | HTR2A (0.35) | ALDH1A1MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL5682299 | 0.81 | MAPK1 (0.41) | ALDH1A1MAPTHTTNPSR1KMT2A | |
| SCHEMBL28194083 | 0.80 | HTR5A (0.31) | HTR2AHTR2C | |
| SCHEMBL28194084 | 0.80 | HTR5A (0.31) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602464-B | Method for preparing biaryl quinoline antibiotics by optical resolution | 宜昌人福药业有限责任公司 | 2020-02-18 | — | — | CN | claimed |
| CN-107602464-B | Method for preparing biaryl quinoline antibiotics by optical resolution | 宜昌人福药业有限责任公司 | 2020-02-18 | — | — | CN | disclosed |
| EP-1227085-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR | TAKEDA PHARMACEUTICAL (JP) | 2006-03-15 | — | — | EP | disclosed |
| US-6800778-B1 | OPTICALLY ACTIVE CYCLIC PHOSPHORUS COMPOUND USED AS REAGENT FOR OPTICAL RESOLUTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| EP-1227085-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |