Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681800 | 0.96 | DRD4 (0.62) | DRD4KDM4EHTR7POLBUSP2 | |
| SCHEMBL7159444 | 0.89 | DRD4 (0.49) | DRD4KDM4EHTR7SLC29A1MCL1 | |
| SCHEMBL5679807 | 0.85 | KDM4E (0.61) | KDM4EPOLBUSP2LMNATHRB | |
| SCHEMBL7158321 | 0.84 | DRD4 (0.52) | DRD4KDM4EHTR7USP2LMNA | |
| SCHEMBL14396763 | 0.83 | DRD4 (0.44) | DRD4KDM4EHTR7POLBSLC29A1 | |
| Fumaric Acid SCHEMBL4772454 | 0.81 | SLC29A1 (0.46) | DRD4POLBSLC29A1MCL1DRD2 | |
| Fumaric Acid SCHEMBL4772459 | 0.81 | SLC29A1 (0.46) | DRD4POLBSLC29A1MCL1DRD2 | |
| SCHEMBL6565335 | 0.80 | KDM4E (0.56) | DRD4KDM4EPOLBUSP2LMNA | |
| SCHEMBL6568492 | 0.80 | TGFBR1 (0.62) | KDM4EPOLBUSP2LMNATHRB | |
| SCHEMBL26126334 | 0.79 | HTR7 (0.59) | DRD4HTR7DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509329-B1 | Inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation | KOWA CO., LTD. (JP) | 2003-01-21 | — | — | US | claimed |
| EP-1403249-B1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | KOWA CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1403249-A1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6509329-B1 | Inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation | KOWA CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |