SCHEMBL4354069

SCHEMBL4354069

Brc1ccc2c(ccc3ccccc32)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.65
ALDH1A1 P00352 5/20 0.61
HSD17B10 Q99714 3/20 0.61
CYP1B1 Q16678 2/20 0.61
HIF1A Q16665 1/20 0.61
HPRT1 P00492 3/20 0.59
TSHR P16473 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
RXFP1 Q9HBX9 1/20 0.55
CYP1A2 P05177 3/20 0.48
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A1 P04798 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646836 0.98 HPRT1 (0.64) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL1527484 0.90 CYP2A6 (0.59) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL723041 0.88 HPRT1 (0.64) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL1527465 0.88 ALDH1A1 (0.64) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL31266523 0.88 ALDH1A1 (0.64) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL8781115 0.87 ALDH1A1 (0.64) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL56836 0.87 CYP2A6 (0.57) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL9068487 0.87 CYP2A6 (0.56) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL2865848 0.86 CYP2A6 (0.67) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL29550755 0.86 CYP2A6 (0.67) CYP2A6ALDH1A1HSD17B10CYP1B1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079735-A Synthesis method of 2-bromophenanthrene 2026-05-26 CN claimed
CN-119462972-A Preparation method of cellulose-based long afterglow material 湖南工业大学 2025-02-18 CN claimed
CN-119064498-A Synchronous rapid detection method for 31 halogenated polycyclic aromatic hydrocarbons in complex cooked food matrix 广东工业大学 2024-12-03 CN claimed
CN-118307471-A Novel azaphenanthrene structural compound and synthesis method thereof 广东工业大学 2024-07-09 CN claimed
CN-117747174-A Anti-radiation wire and preparation method thereof 新凝合科技(成都)有限公司 2024-03-22 CN claimed
CN-114478154-B Industrial synthesis method of picene 西安欧得光电材料有限公司 2023-11-21 CN claimed
CN-115785444-A Inert polyarylene sulfide with aromatic ring as end group, and preparation method and application thereof 中鼎凯瑞科技成都有限公司 2023-03-14 CN claimed
CN-114478154-A Industrial synthesis method of picene 西安欧得光电材料有限公司 2022-05-13 CN claimed
CN-114213444-A Tetraphenylsilane derivative and preparation method thereof 陕西维世诺新材料有限公司 2022-03-22 CN claimed
CN-122079735-A Synthesis method of 2-bromophenanthrene 2026-05-26 CN disclosed
CN-122079735-A Synthesis method of 2-bromophenanthrene 2026-05-26 CN disclosed
CN-122079735-A Synthesis method of 2-bromophenanthrene 2026-05-26 CN disclosed
US-12588407-B2 Organic light-emitting element LG CHEM, LTD. (KR) 2026-03-24 US disclosed
US-20260008745-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2026-01-08 US disclosed
US-20090136768-A1 Hydroxyphenyltriazines With An Aromatic Carbocyclic Fused Ring System CIBA CORPORATION 2009-05-28 US disclosed
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed
US-7348073-B2 Spirocyclopentaphenanthrenefluorene-based compound and organoelectroluminescent device using the same SAMSUNG SDI CO., LTD. (KR) 2008-03-25 US disclosed
CN-1950382-A Organosilanes, process for production of the same, and use thereof SHARP KK (JP) 2007-04-18 CN disclosed
CN-1651368-A Spirocyclopentaphenanthrenefluorene-based compound and organoelectroluminescent device using the same SAMSUNG SDI CO LTD (KR) 2005-08-10 CN disclosed
US-20050158583-A1 Spirocyclopentaphenanthrenefluorene-based compound and organoelectroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2005-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008745-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ITGA1 CYP2A6 1987/4885ALDH1A1 179/4885HSD17B10 2471/4885
US-20090136768-A1 Hydroxyphenyltriazines With An Aromatic Carbocyclic Fused Ring System AHR, PAH, TPH2 CYP2A6 489/4885ALDH1A1 831/4885HSD17B10 2006/4885
US-12588407-B2 Organic light-emitting element LAS1L, LEF1, ARL1 CYP2A6 2105/4885ALDH1A1 135/4885HSD17B10 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.