SCHEMBL5153740

SCHEMBL5153740

CCN(CC)c1cc(C)c(Nc2ccc(C)cc2C)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.36
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 2/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
BRCA1 P38398 1/20 0.34
LMNA P02545 2/20 0.33
CYP3A4 P08684 1/20 0.33
CRHR1 P34998 1/20 0.32
MAPT P10636 3/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
KMT2A Q03164 2/20 0.31
MAPK1 P28482 1/20 0.30
MEN1 O00255 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535472 0.88 ALDH1A1 (0.34) RAPGEF4ALDH1A1HSD17B10HPGDCYP2C9
SCHEMBL6882234 0.87 HPGD (0.34) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL6535277 0.86 ALDH1A1 (0.38) RAPGEF4ALDH1A1HSD17B10HPGDCYP2C9
SCHEMBL7774002 0.83 ALDH1A1 (0.34) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL8977198 0.81 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL9651405 0.81 CYP3A4 (0.40) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL5684606 0.80 RAPGEF4 (0.43) RAPGEF4ALDH1A1HSD17B10HPGDCYP2C9
SCHEMBL10700463 0.80 HPGD (0.36) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL1145120 0.79 ESR1 (0.34) ALDH1A1HSD17B10HPGDCYP2C9ALOX15
SCHEMBL10884503 0.79 LMNA (0.40) RAPGEF4ALDH1A1HSD17B10HPGDCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP claimed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP claimed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO claimed
EP-1390210-B1 METHOD OF MANUFACTURING HEAT SENSITIVE RECORDING MATERIAL AND HEAT SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-01-03 EP disclosed
EP-0680626-A1 PHOTOPOLYMERIZABLE COMPOSITION OF HIGH SENSITIVITY AND METHOD FOR OBTAINING IMAGES THEREWITH AGFA-GEVAERT N.V. (BE) 1995-11-08 EP disclosed
WO-1994017452-A1 PHOTOPOLYMERIZABLE COMPOSITION OF HIGH SENSITIVITY AND METHOD FOR OBTAINING IMAGES THEREWITH AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1994-08-04 WO disclosed
EP-0390432-A2 Color-former NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0345419-A2 Heat-sensitive recording material Toyo Boseki Kabushiki Kaisha (JP) 1989-12-13 EP disclosed