Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681267 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5646002 | 0.89 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5651693 | 0.86 | RAB9A (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5652246 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5649619 | 0.80 | RAB9A (0.66) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5682567 | 0.79 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5681478 | 0.78 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5649597 | 0.76 | RAB9A (0.61) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL25270458 | 0.76 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5651827 | 0.75 | LIPE (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148860-A1 | Substituted p-phenyl carbamates | NOVO NORDISK A/S (DK) | 2006-07-06 | — | — | US | claimed |
| EP-1636188-A1 | PARA-SUBSTITUTED PHENYL CARBAMATES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | claimed |
| WO-2004111006-A1 | PARA-SUBTITUTED PHENYL CARBAMATES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | claimed |
| US-20060148860-A1 | Substituted p-phenyl carbamates | NOVO NORDISK A/S (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1636188-A1 | PARA-SUBSTITUTED PHENYL CARBAMATES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111006-A1 | PARA-SUBTITUTED PHENYL CARBAMATES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148860-A1 | Substituted p-phenyl carbamates | LIPE, PNLIP, LPL | SMN1; SMN2 2599/4885RAB9A 1647/4885NPC1 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.