Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.40 |
| ▸ | S100A10 | P60903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933463 | 0.85 | CA1 (0.55) | CA1CA2CA9IKBKBCHUK | |
| SCHEMBL5682926 | 0.85 | L3MBTL1 (0.44) | CA1CA2CA9IKBKBCHUK | |
| SCHEMBL5677878 | 0.84 | CA2 (0.72) | CA1CA2CA9TSHRSMN1; SMN2 | |
| SCHEMBL30100451 | 0.79 | TSHR (0.51) | CA1CA2CA9TSHRGAA | |
| SCHEMBL1004028 | 0.78 | TSHR (0.58) | CA1CA2CA9TSHRKDM4E | |
| SCHEMBL19439093 | 0.77 | TSHR (0.53) | CA1CA2CA9TSHRKDM4E | |
| SCHEMBL5723934 | 0.77 | KEAP1 (0.56) | CA1CA2CA9TSHRKDM4E | |
| SCHEMBL9367212 | 0.77 | TSHR (0.54) | CA1CA2CA9TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL15690391 | 0.76 | TSHR (0.56) | CA1CA2CA9TSHRKDM4E | |
| SCHEMBL1500536 | 0.75 | TSHR (0.51) | CA1CA2CA9TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633714-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108675-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |