⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28011771 | 0.97 | LPO (0.38) | — | |
| Methane SCHEMBL11818903 | 0.97 | LPO (0.38) | — | |
| Pyridine SCHEMBL28134512 | 0.85 | TSHR (0.36) | — | |
| SCHEMBL30173712 | 0.82 | — | — | |
| SCHEMBL158651 | 0.77 | FBP1 (0.33) | — | |
| SCHEMBL1109685 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL3707993 | 0.72 | — | — | |
| SCHEMBL23418624 | 0.72 | P2RX4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL29837126 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL16992518 | 0.72 | GABRR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101307052-B | Method for preparing pyrrole-N-heterocyclic ring derivates and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2011-08-17 | — | — | CN | claimed |
| EP-2035372-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-03-18 | — | — | EP | claimed |
| CN-101307052-A | Method for preparing pyrrole-N-heterocyclic ring derivates and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2008-11-19 | — | — | CN | claimed |
| WO-2008005338-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | claimed |
| US-5550143-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1996-08-27 | — | — | US | claimed |
| US-4001249-A | CYCLOCOUPLING N-ACYLPYRROLE AND A,A*-HALOGENOKETONE, REDUCING AGENTS | SANWA KAGAKU KENKYUSHO CO. LTD. (JA) | 1977-01-04 | — | — | US | claimed |
| US-3998699-A | PANTIBIOTIC SUBA INSECTICIDES AND ACARICIDESFERMENTING STREPTOMYCES | SANKYO COMPANY LIMITED (JA) | 1976-12-21 | — | — | US | claimed |
| US-3984564-A | Antibiotic substances B-41, their production and their use as insecticides and acaricides | SANKYO COMPANY LIMITED (JA) | 1976-10-05 | — | — | US | claimed |
| US-11772063-B2 | Method and device for producing saccharides and saccharide arrays | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-10-03 | — | — | US | disclosed |
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113461690-B | Synthesis method of chiral 4,6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylate compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| CN-111518105-B | Preparation method of glycocyclo-pyrrole cyclic compound | 华东师范大学 | 2022-11-01 | — | — | CN | disclosed |
| EP-2471796-B1 | NOVEL ADDUCT COMPOUND, SOLUTION FOR FORMATION OF ORGANIC SEMICONDUCTOR FILM, METHOD FOR PRODUCING SAID SEMICONDUCTOR FILM AND METHOD FOR SYNTHESIZING SAID ADDUCT COMPOUND | TEIJIN LTD (JP) | 2019-10-30 | — | — | EP | disclosed |
| CN-108419435-A | Compound and epigenetics for treating cancer | 新加坡科技研究局 | 2018-08-17 | — | — | CN | disclosed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994022868-A1 | 7-AZABICYCLO-[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| US-4112112-A | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect | MERCK & CO., INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4056536-A | CHEMICAL INTERMEDIATES | MERCK & CO., INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-4001249-A | CYCLOCOUPLING N-ACYLPYRROLE AND A,A*-HALOGENOKETONE, REDUCING AGENTS | SANWA KAGAKU KENKYUSHO CO. LTD. (JA) | 1977-01-04 | — | — | US | disclosed |