Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686572 | 0.93 | CASP1 (0.43) | RENCTSBCTSKCTSDBACE1 | |
| SCHEMBL5686581 | 0.93 | CASP1 (0.43) | RENCTSBCTSKCTSDBACE1 | |
| SCHEMBL5686901 | 0.92 | REN (0.46) | RENCTSBCTSKCTSD | |
| SCHEMBL5689425 | 0.87 | CASP1 (0.49) | RENCTSKCTSDBACE1 | |
| SCHEMBL7198017 | 0.86 | REN (0.46) | RENCTSBCTSKCTSD | |
| SCHEMBL5686929 | 0.76 | CASP1 (0.47) | RENCTSBCTSKBACE1 | |
| SCHEMBL8026640 | 0.76 | CASP1 (0.47) | RENCTSBCTSKBACE1 | |
| SCHEMBL5686579 | 0.75 | CTSD (0.38) | CTSD | |
| SCHEMBL5686711 | 0.74 | CTSD (0.36) | CTSDBACE1 | |
| SCHEMBL5686897 | 0.73 | CTSD (0.37) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979241-B1 | (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA | IVAX DRUG RES INST LTD (HU) | 2006-03-01 | — | — | EP | disclosed |
| US-6593300-B1 | Inhibitors of the interleukin-1 beta converting enzyme | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2003-07-15 | — | — | US | disclosed |