Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5687066 | 0.90 | CTSD (0.55) | OPRD1CTSDOPRM1ERAP2OPRK1 | |
| SCHEMBL5687168 | 0.90 | CTSD (0.55) | OPRD1CTSDOPRM1ERAP2OPRK1 | |
| SCHEMBL29944413 | 0.89 | CTSD (0.61) | OPRD1CTSDOPRM1OPRK1 | |
| SCHEMBL29732072 | 0.89 | CTSD (0.61) | OPRD1CTSDOPRM1OPRK1 | |
| SCHEMBL22644029 | 0.88 | OPRD1 (0.55) | OPRD1OPRM1OPRK1CASP1 | |
| SCHEMBL5689768 | 0.86 | CASP1 (0.59) | OPRD1CTSDCASP1 | |
| SCHEMBL31276527 | 0.85 | SLC7A5 (0.56) | OPRD1OPRM1ERAP2OPRK1LNPEP | |
| SCHEMBL9513983 | 0.84 | SLC7A5 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9419218 | 0.84 | SLC7A5 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31265324 | 0.82 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979241-B1 | (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA | IVAX DRUG RES INST LTD (HU) | 2006-03-01 | — | — | EP | disclosed |
| US-6593300-B1 | Inhibitors of the interleukin-1 beta converting enzyme | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2003-07-15 | — | — | US | disclosed |
| EP-0979241-A1 | (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049189-A1 | (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA | Gyógyszerkutató Intézet Kft. (HU) | 1998-11-05 | — | — | WO | disclosed |