Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076666 | 0.77 | MGLL (0.33) | — | |
| SCHEMBL1655594 | 0.76 | MGLL (0.33) | — | |
| SCHEMBL21711270 | 0.74 | KMT2A (0.33) | — | |
| SCHEMBL21711250 | 0.74 | KMT2A (0.33) | — | |
| SCHEMBL16871706 | 0.74 | PTPN2 (0.46) | — | |
| SCHEMBL21711252 | 0.74 | KMT2A (0.37) | — | |
| SCHEMBL21711112 | 0.73 | — | — | |
| SCHEMBL21711249 | 0.72 | MGLL (0.35) | — | |
| Ethylene Glycol SCHEMBL29119578 | 0.71 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21711120 | 0.71 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344634-B2 | Activity based probe and uses thereof for imaging | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-05-31 | — | — | US | disclosed |
| US-11344634-B2 | Activity based probe and uses thereof for imaging | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-05-31 | — | — | US | disclosed |
| EP-3416692-B1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) | 2020-12-16 | — | — | EP | disclosed |
| US-20190054193-A1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-02-21 | — | — | US | disclosed |
| US-20190054193-A1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-02-21 | — | — | US | disclosed |
| EP-3416692-A1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017141251-A1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2017-08-24 | — | — | WO | disclosed |
| WO-2013121284-A1 | IODINATED PRODUCTS INTENDED FOR A USE FOR THE MEDICAL IMAGING AND THEIR METHODS OF PREPARATION | UNIVERSITE DE STRASBOURG (FR) | 2013-08-22 | — | — | WO | disclosed |
| WO-2012018290-A1 | DISCRETE COATED NANOPARTICLES | KEMPE MARIA (SE) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344634-B2 | Activity based probe and uses thereof for imaging | GUSB, CPB1, MPI | HDAC3 1030/4885HDAC4 2023/4885HDAC1 1093/4885 |
| US-20190054193-A1 | ACTIVITY BASED PROBE AND USES THEREOF FOR IMAGING | GUSB, CPB1, MPI | HDAC3 1030/4885HDAC4 2023/4885HDAC1 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.