Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 14/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689707 | 0.88 | NPY4R (0.44) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5686700 | 0.85 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5686852 | 0.82 | OPRD1 (0.43) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5688620 | 0.82 | OPRD1 (0.43) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31380448 | 0.79 | ENPEP (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL5687724 | 0.79 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29892843 | 0.78 | ENPEP (0.52) | OPRD1FNTAFNTBPGGT1B | |
| SCHEMBL5689507 | 0.78 | OPRD1 (0.49) | OPRD1 | |
| SCHEMBL29794105 | 0.78 | OPRD1 (0.59) | OPRD1OPRM1OPRK1CCKARCCKBR | |
| SCHEMBL5686954 | 0.77 | CTSD (0.44) | OPRD1OPRM1OPRK1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979241-B1 | (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA | IVAX DRUG RES INST LTD (HU) | 2006-03-01 | — | — | EP | disclosed |
| US-6593300-B1 | Inhibitors of the interleukin-1 beta converting enzyme | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2003-07-15 | — | — | US | disclosed |