Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688033 | 0.82 | MAPT (0.43) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL5689316 | 0.69 | HRH2 (0.43) | HRH2HRH1ALDH1A1TDP1AKR1C3 | |
| SCHEMBL5072717 | 0.68 | TSHR (0.68) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL28274439 | 0.67 | ALDH1A1 (0.63) | HRH2HRH1ALDH1A1TDP1LMNA | |
| SCHEMBL1638978 | 0.67 | CACNA1D (0.66) | KMT2AALDH1A1TDP1LMNAMAPT | |
| SCHEMBL5076639 | 0.67 | TSHR (0.53) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL3387460 | 0.66 | TSHR (0.69) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL13656495 | 0.65 | HRH2 (0.57) | HRH2HRH1KMT2AALDH1A1TDP1 | |
| SCHEMBL21275707 | 0.65 | TSHR (0.54) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL5324169 | 0.65 | CTSD (0.51) | KMT2AMEN1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635827-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110442-A1 | PYRIDINE N-OXIDES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-12-23 | — | — | WO | disclosed |