SCHEMBL5687971

SCHEMBL5687971

Cc1ccc(Oc2ccc(OCC3CCN(C(=O)Oc4ccc(Cc5ncccc5C)cc4)CC3)cc2)nc1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 9/20 0.48
GRIN2B Q13224 3/20 0.46
ACACB O00763 1/20 0.40
BCHE P06276 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
ACACA Q13085 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5932092 0.93 LIPE (0.47) LIPEGRIN2BACACBBCHECYP4F2
SCHEMBL5688820 0.91 LIPE (0.46) LIPEGRIN2BCYP4F2CYP4A11
SCHEMBL5689967 0.89 LIPE (0.45) LIPEACACBBCHEACACA
SCHEMBL5688501 0.88 LIPE (0.51) LIPEGRIN2BACACBBCHECYP4F2
SCHEMBL5688672 0.86 LIPE (0.52) LIPEGRIN2BACACBBCHECYP4F2
SCHEMBL5690381 0.85 GRIN2B (0.46) LIPEGRIN2BCYP4F2CYP4A11
SCHEMBL5687429 0.85 GRIN2B (0.46) LIPEGRIN2BCYP4F2CYP4A11
SCHEMBL5688364 0.84 LIPE (0.48) LIPEGRIN2BACACBBCHECYP4F2
SCHEMBL5688710 0.84 LIPE (0.47) LIPEGRIN2BACACBCYP4F2CYP4A11
SCHEMBL5687622 0.84 LIPE (0.48) LIPEGRIN2BACACBBCHEACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060160851-A1 Substituted piperidine carbamates NOVO NORDISK A/S (DK) 2006-07-20 US claimed
EP-1636207-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2006-03-22 EP claimed
WO-2004111032-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-12-23 WO claimed
US-20060160851-A1 Substituted piperidine carbamates NOVO NORDISK A/S (DK) 2006-07-20 US disclosed
EP-1636207-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2006-03-22 EP disclosed
WO-2004111032-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160851-A1 Substituted piperidine carbamates LIPE, PNLIP, LIPC LIPE 1/4885GRIN2B 2588/4885ACACB 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.