Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572286 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5688026 | 0.87 | FYN (0.48) | KDM4EALDH1A1MAPTFYNCHEK2 | |
| SCHEMBL6011581 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6011444 | 0.81 | FYN (0.51) | ALDH1A1FYNHSD17B10CHEK2 | |
| SCHEMBL5685016 | 0.81 | ALOX15 (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL6011308 | 0.80 | TUBB4A (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6573114 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL94025 | 0.79 | TSHR (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30167101 | 0.79 | TSHR (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5685506 | 0.79 | MAPK1 (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | disclosed |
| EP-1418879-B1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | KRT18, S100P, ALDH7A1 | KDM4E 497/4885CNR1 2657/4885CNR2 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.