SCHEMBL94025

SCHEMBL94025

COc1ccc(N)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
CYP1A2 P05177 2/20 0.58
CYP3A4 P08684 1/20 0.58
NFKB1 P19838 1/20 0.58
LMNA P02545 2/20 0.56
MEN1 O00255 1/20 0.56
APEX1 P27695 1/20 0.56
KMT2A Q03164 1/20 0.56
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
TP53 P04637 1/20 0.54
CASP1 P29466 1/20 0.52
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 3/20 0.52
AOX1 Q06278 1/20 0.52
USP2 O75604 1/20 0.52
RECQL P46063 1/20 0.52
MAPT P10636 4/20 0.50
GAA P10253 3/20 0.50
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167101 1.00 TSHR (0.58) TSHRCYP1A2CYP3A4NFKB1LMNA
Hydrochloric Acid SCHEMBL27721215 0.98 LMNA (0.59) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL1119364 0.84 MAOB (0.64) TSHRNFKB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL2481394 0.82 MAOB (0.61) TSHRNFKB1LMNAMEN1KMT2A
SCHEMBL1347657 0.81 CASP1 (0.50) TSHRCYP3A4LMNAMEN1KMT2A
SCHEMBL6011308 0.80 TUBB4A (0.46) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL29048794 0.79 ALDH1A1 (0.48) TSHRCYP3A4LMNAMEN1KMT2A
SCHEMBL5688201 0.79 KDM4E (0.50) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL9827407 0.79 TSHR (0.75) TSHRCYP1A2CYP3A4NFKB1LMNA
Hydroxyamine SCHEMBL4369811 0.79 KDM4E (0.62) TSHRCYP1A2CYP3A4LMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2601 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680219-A2 ACETAMINOPHEN COMPOSITIONS AND METHODS OF TREATING CANCER The United States Government as represented by the Department of Veterans Affairs (US) 2026-01-21 EP claimed
EP-4408377-B1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORP (JP) 2025-10-08 EP claimed
US-20240390244-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT KAO CORPORATION (JP) 2024-11-28 US claimed
US-20240390243-A1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORPORATION (JP) 2024-11-28 US claimed
US-20240382394-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE AND AMINE SALT KAO CORPORATION (JP) 2024-11-21 US claimed
WO-2024192214-A2 ACETAMINOPHEN COMPOSITIONS AND METHODS OF TREATING CANCER THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2024-09-19 WO claimed
EP-4408377-A2 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES Kao Corporation (JP) 2024-08-07 EP claimed
CN-118440281-A Polyurethane plastic runway spouted surface material with excellent weather resistance 河南新旭体育设施有限公司 2024-08-06 CN claimed
CN-118119370-A Composition comprising an oxidation dye and a direct dye 花王株式会社 2024-05-31 CN claimed
CN-118055753-A Composition comprising an oxidation dye and an amine salt 花王株式会社 2024-05-17 CN claimed
WO-1997011674-A1 COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME L'OREAL (FR) 1997-04-03 WO claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
EP-0728465-A1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition L'OREAL (FR) 1996-08-28 EP claimed
US-5540738-A SIMULTANEOUSLY APPLYING IODIDE IONS, AN OXIDANT AND AN EFFECTIVE CONCENTRATION OF AN OXIDATION DYE TO PRODUCE INTENSE COLORS IN ALKALINE SOLUTION CHAN ALEXANDER C (US) 1996-07-30 US claimed
EP-0722710-A1 Keratinous fiber oxidation dyeing composition and the dyeing process using this composition L'OREAL (FR) 1996-07-24 EP claimed
EP-0545257-B1 Oxidative hair coloring compositions and process for dyeing human keratinous fibers BRISTOL MYERS SQUIBB CO (US) 1996-05-29 EP claimed
EP-0545257-A2 Oxidative hair coloring compositions and process for dyeing human keratinous fibers BRISTOL-MYERS SQUIBB COMPANY (US) 1993-06-09 EP claimed
US-5180396-A Process for dyeing keratinous fibres with oxidation dyes combined with indole derivatives and dyeing composition employed L'OREAL (FR) 1993-01-19 US claimed
US-5180397-A Hair dyes L'OREAL (FR) 1993-01-19 US claimed
US-4985955-A INTENSE COLORATIONS IN RELATIVELY SHORT TIMES L'OREAL (FR) 1991-01-22 US claimed