Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049024 | 0.85 | KIF11 (0.63) | TRPV4KIF11AR | |
| SCHEMBL1724867 | 0.84 | KIF11 (0.51) | TRPV4KIF11ARGAAKDM4E | |
| SCHEMBL29800340 | 0.83 | FFAR4 (0.39) | TRPV4KIF11ARGAAFFAR4 | |
| SCHEMBL7569957 | 0.81 | TRPV4 (0.58) | TRPV4KIF11ARP4HBMRGPRX4 | |
| SCHEMBL29353872 | 0.80 | FFAR4 (0.37) | TRPV4KIF11ARGAAFFAR4 | |
| SCHEMBL7116955 | 0.80 | KIF11 (0.42) | TRPV4KIF11GAAKDM4EALDH1A1 | |
| SCHEMBL20929103 | 0.80 | FFAR4 (0.37) | TRPV4KIF11ARGAAFFAR4 | |
| SCHEMBL7604551 | 0.79 | TRPV4 (0.56) | TRPV4KIF11ARGAAP4HB | |
| SCHEMBL185191 | 0.78 | KIF11 (0.58) | TRPV4KIF11ARP4HBMRGPRX4 | |
| SCHEMBL10502974 | 0.78 | TRPV4 (0.54) | TRPV4KIF11ARP4HBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1301965-C | Prepn process of 2-trifluoromethyl-4-cyano aniline | DALIAN LUYUAN PHARMACEUTICAL I (CN) | 2007-02-28 | — | — | CN | claimed |
| CN-1740147-A | Prepn process of 2-trifluoromethyl-4-cyano aniline | DALIAN LUYUAN PHARMACEUTICAL I (CN) | 2006-03-01 | — | — | CN | claimed |
| JP-10204066-A | — | — | None | — | — | JP | disclosed |
| US-20260090265-A1 | COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGE SENSOR, PHOTOSENSOR AND SOLID-STATE IMAGING APPARATUS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-26 | — | — | US | disclosed |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2025-06-05 | — | — | US | disclosed |
| CN-119930443-A | Method for synthesizing trifluoromethyl substituted aniline by using tetradentate platinum complex as photocatalyst | 九洲药业(杭州)有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114206870-B | Tricyclic AKR1C 3-dependent KARS inhibitors | 诺华股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-20240262827-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2024-08-08 | — | — | US | disclosed |
| WO-2024135508-A1 | COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE | 三菱瓦斯化学株式会社 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024126619-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE | NOVALED GMBH (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-4065117-B1 | ISOQUINOLINE DERIVATIVES FOR USE IN TREATING GLUT1 DEFICIENCY SYNDROME | GLIAPHARM SA (CH) | 2024-06-19 | — | — | EP | disclosed |
| US-6362372-B2 | HYDROGENATION OF A TRIFLUOROBENZYLNITRILE BY HYDROGEN IN AN ORGANIC SOLVENT IN THE PRESENCE OF AMMONIA AND A CATALYST COMPRISING A PLATINUM GROUP ELEMENT; EXTREMELY HIGH YIELDS | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| US-6175041-B1 | HYDROGENATING A TRIFLUOROMETHYLBENZONITRILE WITH HYDROGEN IN AN ORGANIC SOLVENT IN THE PRESENCE OF AMMONIA, USING A RANEY CATALYST | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5981438-A | HERBICIDE, INSECTICIDE AND PESTICIDE | NIHON BAYER AGROCHEM K.K. (JP) | 1999-11-09 | — | — | US | disclosed |
| CN-1194267-A | 1-phenyl-5-anilinotetrazole compounds | BAYER AGROCHEM KK (JP) | 1998-09-30 | — | — | CN | disclosed |
| JP-H10204066-A | 1-PHENYL-5-ANILINOTETRAZOLES AND THEIRS UTILIZATION AS AGROCHEMICAL | NIPPON BAYER AGROCHEM KK | 1998-08-04 | — | — | JP | disclosed |
| EP-0855394-A1 | 1-Phenyl-5-anilinotetrazoles derivatives, their preparation and their use as microbiocides, insecticides and/or herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-4153687-A | Derivatives, having an inhibitory action against protease and an antiphlogistic action, of the trypsin-kallikrein inhibitor obtained from cattle organs (BPTI), their preparation and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | disclosed |
| US-4059402-A | SUBLIMATION, MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | IDH1, INMT, TH | TRPV4 4031/4885KIF11 2157/4885AR 3622/4885 |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | AKR1C2, AKR1B1, AKR1C1 | TRPV4 3597/4885KIF11 571/4885AR 220/4885 |
| US-20260090265-A1 | COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGE SENSOR, PHOTOSENSOR AND SOLID-STATE IMAGING APPARATUS | SLC43A1, CNPY2, SCO2 | TRPV4 508/4885KIF11 3758/4885AR 2057/4885 |
| US-20240262827-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | AKR1C2, AKR1B1, AKR1C1 | TRPV4 3597/4885KIF11 571/4885AR 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.