Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971664 | 0.93 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27788183 | 0.93 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23754643 | 0.90 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7715736 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27735819 | 0.86 | TSHR (0.71) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5686979 | 0.84 | TSHR (0.74) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5686970 | 0.84 | TSHR (0.74) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15062349 | 0.84 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5836895 | 0.83 | TSHR (0.67) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8699776 | 0.83 | TSHR (0.67) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111747-B | A kind of ketoxime removing type room temperature vulcanized silicone rubber of self-catalysis and preparation method thereof | 山东大学 | 2018-06-19 | — | — | CN | disclosed |
| EP-0978525-B1 | Acryloxypropyl or methacryloxypropyl group containing siloxane oligomers | DEGUSSA (DE) | 2006-03-01 | — | — | EP | disclosed |
| US-20040210015-A1 | AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS | SONNENSCHEIN MARK F (US) | 2004-10-21 | — | — | US | disclosed |
| EP-0978525-A2 | Acryloxypropyl or methacryloxypropyl group containing siloxane oligomers | Degussa-Hüls Aktiengesellschaft (DE) | 2000-02-09 | — | — | EP | disclosed |