SCHEMBL5689964

SCHEMBL5689964

Cn1nnnc1SC1CCN(C(=O)Oc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 17/20 0.67
BCHE P06276 1/20 0.60
SCN9A Q15858 1/20 0.44
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5690539 0.88 LIPE (0.60) LIPEBCHE
SCHEMBL5687645 0.88 LIPE (0.67) LIPEBCHESCN9A
SCHEMBL5689572 0.87 LIPE (0.59) LIPEBCHESCN9AMAPTHTT
SCHEMBL5688597 0.87 LIPE (0.48) LIPEBCHEMAPTLMNA
SCHEMBL5687394 0.87 LIPE (0.61) LIPEBCHESCN9AMAPTHTT
SCHEMBL5691970 0.86 LIPE (0.48) LIPEBCHE
SCHEMBL5689143 0.85 LIPE (0.68) LIPEBCHESCN9AMAPTHTT
SCHEMBL5931993 0.85 LIPE (0.59) LIPEBCHESCN9AMAPTHTT
SCHEMBL5688143 0.84 LIPE (0.44) LIPEBCHEMAPTHTT
SCHEMBL5690408 0.83 LIPE (0.71) LIPEBCHESCN9AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060160851-A1 Substituted piperidine carbamates NOVO NORDISK A/S (DK) 2006-07-20 US claimed
EP-1636207-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2006-03-22 EP claimed
WO-2004111032-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-12-23 WO claimed
US-20060160851-A1 Substituted piperidine carbamates NOVO NORDISK A/S (DK) 2006-07-20 US disclosed
EP-1636207-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2006-03-22 EP disclosed
WO-2004111032-A1 SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160851-A1 Substituted piperidine carbamates LIPE, PNLIP, LIPC LIPE 1/4885BCHE 32/4885SCN9A 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.