Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indene SCHEMBL29746662 | 0.89 | CYP2D6 (0.51) | CYP2D6CYP2C19NPC1RAB9ACA2 | |
| Indene SCHEMBL89373 | 0.89 | CYP2D6 (0.51) | CYP2D6CYP2C19NPC1RAB9ACA2 | |
| Indene SCHEMBL27887053 | 0.87 | CYP2D6 (0.50) | CYP2D6CYP2C19NPC1RAB9ACA2 | |
| Indene SCHEMBL28769797 | 0.87 | CYP2D6 (0.50) | CYP2D6CYP2C19NPC1RAB9ACA2 | |
| Indene SCHEMBL28869263 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP2C19SMN1; SMN2NPC1RAB9A | |
| Indene SCHEMBL6700608 | 0.85 | CA2 (0.47) | CYP2D6CYP2C19MAPTALDH1A1CA2 | |
| Indene SCHEMBL30959780 | 0.85 | CA2 (0.47) | CYP2D6CYP2C19MAPTALDH1A1CA2 | |
| Indene SCHEMBL2769732 | 0.83 | CYP2D6 (0.53) | CYP2D6CYP2C19HPGDLMNAALDH1A1 | |
| Indene SCHEMBL368620 | 0.83 | CYP2D6 (0.72) | CYP2D6CYP2C19SMN1; SMN2MAPTNPC1 | |
| Indene SCHEMBL28216169 | 0.81 | CA1 (0.50) | CYP2D6CYP2C19CA2CA1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105654-A | Curable resin mixture, curable resin composition, and cured product thereof | 日本化药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2020031935-A1 | CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT | 日本化薬株式会社 | 2020-02-13 | — | — | WO | disclosed |
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |