Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.58 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.48 |
| ▸ | ITGAV | P06756 | 6/20 | 0.48 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070239 | 0.86 | FKBP1A (0.61) | ITGB1ITGA5ITGA4FKBP1ACCR4 | |
| SCHEMBL5690343 | 0.85 | ITGB1 (0.53) | ITGB1ITGA5ITGA4ITGAVMAPT | |
| SCHEMBL5690462 | 0.83 | ITGB1 (0.63) | ITGB1ITGA5ITGA4ITGAVITGB7 | |
| SCHEMBL5691025 | 0.83 | ITGB1 (0.63) | ITGB1ITGA5ITGA4ITGAVITGB7 | |
| SCHEMBL5691033 | 0.81 | ITGB1 (0.58) | ITGB1ITGA5ITGA4ITGAVITGB7 | |
| SCHEMBL7707493 | 0.79 | ITGB1 (0.60) | ITGB1ITGA5ITGA4FKBP1AITGB7 | |
| SCHEMBL6429533 | 0.78 | ITGB1 (0.52) | ITGB1ITGA5ITGA4FKBP1AITGAV | |
| SCHEMBL5690244 | 0.78 | ALDH1A1 (0.56) | ITGB1ITGA5ITGA4FKBP1AITGAV | |
| SCHEMBL5691845 | 0.78 | MAPT (0.50) | ITGB1ITGA5MAPT | |
| SCHEMBL27565203 | 0.77 | ITGB1 (0.63) | ITGB1ITGA5ITGA4FKBP1AITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |