Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | YAP1 | P46937 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691845 | 0.93 | MAPT (0.50) | ITGB1ITGA5MAPK1STSYAP1 | |
| SCHEMBL5690885 | 0.86 | ITGB1 (0.58) | ITGB1ITGA5MAPK1PTPN2PTPN1 | |
| SCHEMBL5690351 | 0.85 | ITGB1 (0.58) | ITGB1ITGA5ITGAVITGA4MAPT | |
| SCHEMBL6429533 | 0.82 | ITGB1 (0.52) | ITGB1ITGA5YAP1ITGAVCMA1 | |
| SCHEMBL7070239 | 0.82 | FKBP1A (0.61) | ITGB1ITGA5ITGA4 | |
| SCHEMBL6165579 | 0.81 | MAPK1 (0.75) | MAPK1STSYAP1KMT2A | |
| SCHEMBL6165580 | 0.81 | MAPK1 (0.75) | MAPK1STSYAP1KMT2A | |
| SCHEMBL5690979 | 0.80 | ALDH1A1 (0.53) | ITGB1ITGA5MAPK1YAP1ITGAV | |
| SCHEMBL5690719 | 0.80 | ITGB1 (0.57) | ITGB1ITGA5MAPK1ITGAVITGA4 | |
| SCHEMBL5691083 | 0.80 | ITGB1 (0.48) | ITGB1ITGA5ITGAVCMA1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |