Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688692 | 0.88 | CYP17A1 (0.40) | CYP17A1CYP3A4ACSS2SIRT2 | |
| SCHEMBL5688583 | 0.86 | CYP17A1 (0.56) | CYP17A1CYP3A4SIRT2ATM | |
| SCHEMBL5688662 | 0.85 | CYP17A1 (0.40) | CYP17A1CYP3A4ACSS2KITSIRT2 | |
| SCHEMBL5688704 | 0.84 | CYP17A1 (0.44) | CYP17A1CYP3A4ACSS2SIRT2ATM | |
| SCHEMBL4031099 | 0.84 | CYP17A1 (0.52) | CYP17A1CYP3A4ACSS2SIRT2 | |
| SCHEMBL5688555 | 0.82 | CYP17A1 (0.48) | CYP17A1CYP3A4FGFR1FGFR3 | |
| SCHEMBL5688570 | 0.82 | CYP17A1 (0.48) | CYP17A1CYP3A4ACSS2FGFR1FGFR3 | |
| SCHEMBL5688707 | 0.79 | CYP17A1 (0.40) | CYP17A1CYP3A4SIRT2 | |
| SCHEMBL5690999 | 0.79 | SIRT2 (0.33) | CYP17A1CYP3A4SIRT2 | |
| SCHEMBL5689004 | 0.78 | CYP17A1 (0.44) | CYP17A1CYP3A4RORCSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |