Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20243055 | 0.98 | NOS1 (0.38) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL7199828 | 0.92 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27596147 | 0.92 | CA12 (0.38) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| Hydrochloric Acid SCHEMBL28464794 | 0.90 | CA12 (0.37) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL66234 | 0.89 | SLC7A5 (0.50) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL66233 | 0.89 | SLC7A5 (0.50) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL2541315 | 0.89 | SLC7A5 (0.50) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL2368385 | 0.87 | NOS1 (0.39) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| SCHEMBL22036228 | 0.87 | NOS1 (0.36) | NOS1NOS3NOS2LTA4HSLC7A5 | |
| Hydrochloric Acid SCHEMBL953367 | 0.87 | SLC7A5 (0.48) | NOS1NOS3NOS2LTA4HSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970586-B1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORP (US) | 2022-12-07 | — | — | EP | disclosed |
| EP-2968231-B1 | ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-07-01 | — | — | EP | disclosed |
| EP-2968231-A1 | ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT | Merial, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970586-A1 | AMINE FUNCTIONAL POLYAMIDES | Genzyme Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150451-A1 | ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT | MERIAL LIMITED (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014150338-A1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | MMP9, MMP26, MMP25 | NOS1 2003/4885NOS3 1799/4885NOS2 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.